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Dr. B. Lal Institute of Biotechnology

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Biotechnology, a world of new inventions, creations and bonding with nature and environment had upgraded the living of humans on earth. Biotechnology is a study where technology and biological systems come together to develop or make products for a specific use. 

Biotechnology contains a number of technologies based upon biological understanding at the cellular and molecular level. It is believed that Biotechnology had a much more significant role in the 21st century than it had in the 20th century. The 21st century opened various avenues for research aspirants in fields of medicine, pharmaceuticals, and agriculture.

With the ever-increasing achievements like the breaking of the genetic code and the development of tools that enable scientists to probe the molecules of life, the 21st-century Biotechnology is the amalgamation of these developments with computer powers as in Bioinformatics,   to help face the upcoming challenges.

Agricultural based companies had interest ranging from tissue culture to biopesticides. Major attention had been given by the health-related activities like the Antimicrobial Stewardship Program and in environmental biotechnology. The biopharmaceutical, which comprises of vaccines, diagnostics, and recombinant products, is the major segment of the Indian Biotechnology Industry.

The Department of Biotechnology (DBT), Council of Scientific and Industrial Research (CSIR), Indian Council of Medical Research (ICMR), Indian Council of Agricultural Research (ICAR), the University Grants Commission (UGC) and the Department of Scientific and Industrial Research (DSIR) are the six major agencies responsible for financing and supporting research in the realm of biotechnology. Biotechnology with remarkable changes and developments lead to the path full of many opportunities and challenges.


Biotechnology is a cross-cutting technology encountered is wide application across several sectors of development. Biotechnology makes important contributions to the new knowledge-based economy and makes in a variety of disciplines.

Challenges are faced by all developing countries is setting up the agendas of international cooperation is deriving benefits biotech markets. Hence, important elements in the use of biotechnology for development are education & capacity building schemes. These help developing countries to embark on sustainable development.

Developing countries are devising and using strategic technologies to solve problems of local, regional and global significance. Their participation in several regional & international pedigree programmers contributes to an on-stream worldwide resource that reflects the human face of globalization.

Also, it is time for developing countries to become more proactive in identifying their strengths, competencies & weaknesses is setting the agenda & speed in harnessing biotechnology for their own scientific & national development.


The environment is an important component necessary for the existence of both mankind and other biotic organisms. The degree of sustainability of the physical environment is an index of the survival and well-being of the entire components in it.

But, human’s activities in his environment involve a lot of chemical synthesis in the process of converting the natural products in his environment into other forms convenient for his utility. In the process of creating products, the man also creates problems either consciously or unconsciously vis-à-vis pollution. The most acceptable solution to the generated wastes in the environment is such that will conveniently integrate them back into the environment.

That method involves the use of microorganisms—usually yeasts, bacteria, or fungi as a whole cell usage production system or in the form of industrial enzymes. In many cases these microorganisms or their products are integrated into the substrates which give us the products, desired in the industries, examples of these are bioleaching (biomining), bio detergent, biotreatment of pulp, biotreatment of wastes (bioremediation), biofiltration, aquaculture treatments, biotreatment of textiles, biocatalysts, biomass fuel production, biomonitoring, and so forth. These are tools (biotechnological tools), which could solve the problem of pollution and help sustain the environment.

This is so because when the products or their constituents are discarded, they go back into the ecosystem. As such, they become reconverted into organic components of the environments. Moreover, their production is strictly biological instead of chemical.


Being a student and highly interested in research can feel counter-intuitive to most but, it is not in fact! Research is more productive when done with an open and fertile mind. Acknowledging this fact already, there have been worldwide measures to promote budding researchers and to “catch them young”. Pragmatically one can ponder if by choosing research one can be sustained in this competitive and capitalistic economy.

In order to thrive in the field of research these days, there is a requirement of intuition, good scientific basics, analytical skills, passion and ability to approach a solution using widely different methods. In addition to the aptitude, Biotechnology provides one such advantage to do research.

Research areas in Biotechnology include genetics, genomics, bioinformatics, plant and animal biotechnology, medical biotechnology, Biotechnology in environment and biodiversity sustenance, biofuel development, product and process development, bio-instrumentation, human resource development, and biosafety, etc. It has applications today in approaching questions pursued in the field of physics, chemistry, mechanical engineering, aviation, artificial intelligence, pharmaceuticals, textile, food industry, etc.

Research areas

Today, the potential areas of research in Biotechnology have become so vast and mind-boggling that it is not possible to make a conclusive and comprehensive list. Further, new areas of study are continuously emerging. To have an overview here are a few fields where biotechnology plays out as a significant tool:

  1. a) Agriculture -used for producing transgenics of rice, wheat, cotton, potato, and vegetables giving higher productivity. b) Basic research: Applying aspects of molecular biology, genetics, genomics, proteomics, and neurosciences. c) Bioengineering of biofuels like ethanol, Bio-fertilizers and bio-pesticides d) Bioinformatics: Algorithm design and development, software and tools for data mining and data warehousing applications, Biological Data Curation, phylogenetics having applications in medicine, etc. d) Development of diagnostics: For major diseases, genetic disorders, cancer, tuberculosis, HIV, malaria, and neurological disorders. And low-cost therapeutics: developing new vaccines, diagnostics, drugs and drug delivery system; to produce low-cost, small proteins and therapeutics using plants and animals as bioreactors e) Marine resources f) Neurosciences: neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and motor neuron disease, which would cover study of molecular genetics of these disorders. Neuro-AIDS, autism, and dyslexia. Neuro-informatics, neuron networks, etc. g) Plant tissue culture: providing tissue culture technology at the grassroots level to cover the most plant rich regions of the country which need massive afforestation and wasteland recovery. Utilization of tissue culture for enrichment of genetic diversity. Genetic manipulation of cell culture in forestry for disease resistance and reduction of regeneration time.

There are many Research institutes in India where research can be pursued like:

Agharkar Research Institute, Pune; Anna University, Chennai (www.annauniv.edu); Banaras Hindu University, Varanasi (www.bhu.ac.in); the Birla Institute of Technology and Science, Pilani (www.bits-pilani.ac.in); Bose Institute, Kolkata (www.boseinstitute.org); the Cochin University of Science and Technology (www.cusat.ac.in); Delhi University Campus ; Goa University (www.unigoa.ac.in); ICGEB : International Centre for Genetic Engineering and Biotechnology, New Delhi (www.icgeb.trieste.it); IIT, Kharagpur (www.iitkgp.ernet.in); IIT Kanpur (www.iitk.ac.in); IIT Roorkee (www.iitr.ernet.in); the Indian Institute of Chemical Biology, Kolkata (www.iicb.res.in); the Indian Institute of Science, Bengaluru (www.iisc.ernet.in); Industrial Toxicology Research Centre, Lucknow (www.itrcindia.org); Institute for Stem Cell Biology and Regenerative Medicine, TIFR, Bengaluru (http://instem.res.in); the Institute of Bioresources and Sustainable Development, Imphal (ibsd-imphal.nic.in); the Institute of Genomics and Integrative Biology, New Delhi (www.igib.res.in); IMTECH, Chandigarh (www.imtech.res.in); JNCASR, Bengaluru (www.jncasr.ac.in); the Tata Institute of Fundamental Research, Mumbai (www.tifr.res.in); TERI University, New Delhi (www.teriuniversity.ac.in) and many more.

Within Jaipur You will Find the Following Institutes Where the Research is Actively Pursued:

Birla Institute Of Scientific Research, BISR (http://www.bisr.res.in/); Rajasthan Agricultural Research Institute Durgapura, RARI (http://raridurgapura.org/) and Dr. B. Lal Institute of Biotechnology, BIBT (https://www.blalbiotech.com/), etc.

If you are a student fresh out of school in Jaipur and wondering how and where you can enjoy being a researcher, BIBT is an institute where even at bachelors level you get exposed to research in biotechnology. UG and PG students have their own research questions and projects where they gain hands-on experience and the taste of research. I addition to becoming experts in a particular field in biotechnology, students also have access to learning techniques of other streams of biotechnology through many IBT training modules like molecular biology, food biotechnology, medical microbiology, plant biotechnology, molecular diagnostics, etc.


Biotechnology is the broad area applied to biology and other research areas which include Genomics, Plant and Animal Biotechnology, Medical Biotechnology, Environment and Biodiversity, Bioinformatics, Product and Process Development, Biofuels, Bioinstrumentation, Human Resource development, and Biofuels.

Biotechnology utilizes biomolecular and cellular processes that help to create products and technologies which improve our lives. Recent biotechnology develops breakthrough technologies to fight diseases, feed the hungry, use less and cleaner energy, reduce our environmental harm, have safer, cleaner and more efficient industrial manufacturing processes.

Till today, more than 250 biotechnology health care products and vaccines have been made available to patients. Agricultural biotechnology is used by more than 13.3 million farmers around the world and is used to prevent plants from damage by insects and pests increase yields, and reduce damage done on environment due to farming.

To reduce the toxic chemical pollution and greenhouse gas emissions, new industrial and environmental biotechnology advances have been made.

Other than this, renewable biofuels from algae and use of other cellulosic materials decrease greenhouse gases as well as reducing our dependence on oil. Substitute for petroleum-based plastics, replacing waste destined for a landfill with biodegradable, compostable consumer products is accomplished by the help of Bioplastic, another product that is available today.

“Feeding the world will be one of the greatest challenges of the 21st century. It will be impossible without using scientific advancements and biotechnology.”

 


Knowledge and memories are all that we take to our graves. Hence, it is imperative to assure the quality of both during our lifetime. Education plays a very important role in shaping the former, and the time spent in pursuing it in the latter.

Although basic education is a fundamental right of every living person, few get the opportunity and even fewer are blessed enough to pursue higher education. By the time a student has decided what course to pursue at the masters level, one has a vague idea of what opportunities lay ahead. However, more often than not, the contacts and public relation skills developed at this stage impact the nature of the future work taken up by the student. These life-skills sometimes have a greater impact on the personality of the student which along with knowledge helps to steer their careers in the right direction.

In short, the quality of education at the Master’s level should ensure that each graduating student is indeed a master of his field. They should be provided with the skills to encash their two years of study.  In addition, the student should also be made aware of the benefits of multi-tasking and encouraged to work as they study. Part-time teaching or part time working in labs is one way of inculcating a sense of responsibility as well as satisfaction in them. Also, a practical exposure to current high-end techniques and their applications in industries or RnD will better equip them for the life after Masters.

Apart from these, each and every student should be made aware that unlike the commerce lines, science has several restrictions in terms of pay as well as options within India. Hence, instead of feeling discouraged they should receive professional guidance to help build up their professional resume and develop communication skills that will help them with prospective employers- in research, academia or industry.

Last but not the least; practical bioinformatics is an indispensible skill-set that each and every student should take with them. Today, an amalgamation of both wet and dry-lab skills and data are necessary for meaningful research which ultimately affects all the avenues that one may choose to pursue. Of note, a willingness to try out different things, a risk-taking capacity as well as the mind-set to positively accept failure and lead a balanced life is necessary, especially for those who wish to pursue research in the long-term. The ability to work amicably in a team and honing their ability to read and analyse data and scientific literature are also better learnt at this stage of their education.

With the best faculty mentoring every batch of U.G or P.G. students with its Guru-Shishya Parampara, Dr. B.Lal Institute of Biotechnology has been successfully churning out batch after batch of distinguished biotechnocrats.


The days of manual practice and limited application are over. Diseases are no more affecting crops and productivity of agriculture has reached a high. Toxic metal sequestration has been made possible using microbes. Bio-diesel has been produced in large quantities. Vaccines are available for deadly diseases and proteins vital for a healthy human have been synthesized on large scale. New drugs have been formulated against pathogenic microflora and diagnosis of infections and diseases is quick and accurate. All the aforementioned developments are a part of revolution that has been triggered by Biotechnology. With branches that include medical microbiology, food microbiology, nanotechnology, immunotechnology, plant biotechnology and molecular diagnostics, the spectrum of Biotechnology is colossal. Dr. B. Lal Institute of Biotechnology is amalgamated in this pyramid of constructive impact.

The journey of Dr. B. Lal Institute of Biotechnology over the past decade has been enriched by success and unparalleled recognition. Lot of motivation has been provided by the temple of knowledge called Dr. B. Lal Institute of Biotechnology to students for knowing the subject and to faculty for inspiring students. The faculty of this institute is dedicated to providing sacrosanct knowledge to scholars of the future. Research and curriculum based education are simultaneously provided which is a unique point of the organisation. The beautiful environment and rainbow of biotechnology in which this place is cocooned are worth saluting for many years to come.


“The secret of change is to focus all of your energy, not on fighting the old, but on building the new.” -Socrates, Greek Philosopher

Biotechnology in today’s technology driven world is not only about Biology shaking hands with technology. Its way more than just relating medical terms with applied sciences. Biotechnology is also about bringing unprecedented changes in technological and industrial life of 21st century.

There is no such thing as an “ideal” entrepreneur – a successful entrepreneur can be analytical or insightful, risk-averse or thrill seeking, or expressive and taciturn. As these two thoughts come together in my mind, I see no reason why entrepreneurship in Biotechnology can’t be termed as new era in development of Biotechnology sector.

Commercial biotechnology is highly dependent upon the science base, more so, perhaps, than any other business sector. So, making life less hard for the bio-entrepreneur is extremely important to ensure good ideas get from “the bench to the bedside.”

IT-BT boom in the past 10 years resulted in creation of hypes with hope of a number of new ideas in Biotech industries. Opportunities exist in research & development, production & manufacturing, quality control & analysis, technology transfer. Thus, its time that budding biotechnocrats step out of the well-equipped technical laboratories and put their skills and knowledge to build something out of the box which can revolute the biotech industry. This brings me to highlight one famous phrase which always foster a spark in me –

“The secret of getting ahead is getting started.”-Mark Twain, Writer

Talking about entrepreneurship in Biotechnology and not mentioning Kiran Majumdar-Shaw is as incomplete as rainfall without a rainbow.

She is the chairman and managing director of Biocon Limited, a biotechnology company based in Bangalore (Bengaluru). When she founded Biocon in 1978, it was a small industrial-enzymes company. She spent a brief period as a Trainee Manager at Biocon Biochemicals Limited, of Cork, Ireland, to learn more about the business. Later on, she spearheaded Biocon’s evolution from an industrial enzymes manufacturing company to a fully integrated bio-pharmaceutical company with a well-balanced business portfolio of products and a research focus on diabetes, oncology and auto-immune diseases.

It’s just one example illuminating the fact that how biotechnocrats are the best minds to put forward a thought lead it through an idea and then execute it to business-wise perfection. In fact, the list goes on and on!

By:

Juhi Saxena

Faculty

Dr. B. Lal Institute of Biotechnology